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What makes a great clinical trial in physiotherapy?
Joshua R Zadro1, Anita B Amorim1,2, Giovanni Ferreira1
1School of Public Health, Faculty of Medicine and Health, Institute for Musculoskeletal Health, University of Sydney and Sydney Local Health District, Camperdown, Australia.
Physiotherapy Theory and Practice
|January 4, 2021
Summary
Landmark physiotherapy trials, including those in top journals, show higher quality scores, larger sample sizes, and more citations than typical trials. These characteristics can guide future high-impact physiotherapy research.
Area of Science:
- Physiotherapy research
- Clinical trial methodology
Background:
- High-quality physiotherapy clinical trials are crucial for evidence-based practice.
- Understanding the characteristics of landmark trials can inform future research design.
Purpose of the Study:
- To identify common characteristics of landmark physiotherapy clinical trials.
- To compare landmark trials with a broader sample of physiotherapy research.
Main Methods:
- Comparison of Physiotherapy Evidence Database (PEDro) top five trials against 91 trials in top medical journals and 99 random PEDro trials.
- Analysis of characteristics including PEDro score, sample size, registration, outcomes, citations, and author metrics.
- Statistical analysis using ANOVA and Chi-squared tests for group differences.
Main Results:
- Landmark trials and those in top journals exhibit higher PEDro scores, larger sample sizes, and more study sites.
- These trials receive more citations, are more likely to be prospectively registered, and less likely to report positive findings.
- Authors of landmark trials also have higher publication and citation counts.
Conclusions:
- Physiotherapy trials published in top journals and those highly ranked on PEDro share distinct characteristics.
- These features offer valuable insights for designing, conducting, and reporting future physiotherapy clinical trials.
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