Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nondisjunction01:21

Nondisjunction

4.5K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
4.5K
Nondisjunction01:29

Nondisjunction

80.5K
During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
80.5K
Structural Joints: Fibrous Joints01:03

Structural Joints: Fibrous Joints

3.2K
Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
3.2K
Structural Joints: Cartilaginous Joints01:17

Structural Joints: Cartilaginous Joints

3.4K
As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary...
3.4K
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

5.6K
Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
5.6K
Meiosis I01:49

Meiosis I

203.9K
Meiosis is a carefully orchestrated set of cell divisions, the goal of which—in humans—is to produce haploid sperm or eggs, each containing half the number of chromosomes present in somatic cells elsewhere in the body. Meiosis I is the first such division, and involves several key steps, among them: condensation of replicated chromosomes in diploid cells; the pairing of homologous chromosomes and their exchange of information; and finally, the separation of homologous chromosomes by...
203.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

WAFER Trial: A randomized controlled trial comparing Wide-awake Local Anesthesia No Tourniquet (WALANT) to General and Regional Anesthesia with tourniquet for Flexor Tendon Repair.

Plastic and reconstructive surgery·2026
Same author

Diagnostic performance of photoplethysmography for early vascular compromise in a customisable<i>in vitro</i>flap model.

Medical engineering & physics·2026
Same author

Secondary breast reconstruction using a cross-chest profunda artery perforator flap in a vessel-depleted chest: A case report.

JPRAS open·2026
Same author

A multipurpose flowing vascular phantom for microsurgical training and flap-monitoring research.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2026
Same author

Versatile Application of the Medial Femoral Condyle Free Flap: A 10-year Experience.

Plastic and reconstructive surgery. Global open·2026
Same author

Laparoscopic Total Extraperitoneal Deep Inferior Epigastric Perforator Flap Harvest: First Experience in the United Kingdom and Technical Guidance.

Plastic and reconstructive surgery. Global open·2026
Same journal

Single-stage minimally invasive resection of synchronous left atrial myxoma and pulmonary atypical carcinoid: case report.

Journal of surgical case reports·2026
Same journal

Laparoscopic management of aortofemoral graft erosion into the sigmoid colon following secondary aortoenteric fistula: a case report.

Journal of surgical case reports·2026
Same journal

Intraductal papillary mucinous neoplasm-derived pancreatic cancer of the ventral duct in patient with pancreas divisum: a case report.

Journal of surgical case reports·2026
Same journal

A giant 31-cm pancreatic mucinous cystic neoplasm: a 4-year progression and surgical challenge.

Journal of surgical case reports·2026
Same journal

Well-leg compartment syndrome after orthopedic surgery in the hemi-lithotomy position: a three-case series and literature review.

Journal of surgical case reports·2026
Same journal

Gastric perforation mimicking acute cholecystitis: a case report.

Journal of surgical case reports·2026
See all related articles

Related Experiment Video

Updated: Nov 23, 2025

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

1.4K

Syndactyly.

Luke Geoghegan1, Billie Georgina Knowles2, Dariush Nikkhah3

  • 1Section of Vascular Surgery, Imperial College London Department of Surgery and Cancer, London, UK.

Journal of Surgical Case Reports
|January 4, 2021
PubMed
Summary
This summary is machine-generated.

This case report discusses simple syndactyly, a common congenital condition where fingers or toes are joined. The review covers its occurrence, related conditions, and treatment options for this limb difference.

More Related Videos

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
09:13

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery

Published on: October 6, 2022

3.7K
Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

1.7K

Related Experiment Videos

Last Updated: Nov 23, 2025

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms
08:32

Author Spotlight: Advancing Tendon Research by Developing Mouse Assembloids to Understand Cellular Mechanisms

Published on: March 22, 2024

1.4K
Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery
09:13

Polytetrafluoroethylene PTFE as a Suture Material in Tendon Surgery

Published on: October 6, 2022

3.7K
Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

1.7K

Area of Science:

  • Orthopedics
  • Clinical Genetics
  • Developmental Biology

Background:

  • Syndactyly is a congenital limb malformation characterized by the fusion of digits.
  • Simple syndactyly involves the fusion of skin and soft tissues only, distinguishing it from complex syndactyly which may involve bone fusion.
  • It is one of the most common congenital hand anomalies, with varying incidence rates reported globally.

Observation:

  • This article presents a clinical case of simple syndactyly.
  • The case highlights the typical presentation and diagnostic considerations for this condition.
  • Detailed clinical observations are provided to illustrate the characteristics of simple syndactyly.

Findings:

  • The incidence of simple syndactyly varies, with some studies suggesting a prevalence of 1 in 2,000 to 1 in 3,000 live births.
  • Syndactyly can occur in isolation or as part of various genetic syndromes, necessitating a thorough evaluation for associated anomalies.
  • Management strategies range from conservative observation to surgical separation, depending on the severity and functional impact.

Implications:

  • Early diagnosis and appropriate management are crucial for optimizing functional outcomes and cosmetic appearance.
  • Understanding the genetic associations of syndactyly aids in genetic counseling and the identification of potential underlying syndromes.
  • This case and review contribute to the existing literature, providing valuable insights for clinicians managing patients with syndactyly.