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Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse
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COVID-19 Induced Myocarditis: A Rare Cause of Heart Failure

Qasim Z Iqbal1, Muhammad Adnan Haider2, Saud Bin Abdul Sattar1

  • 1Internal Medicine, Northwell Health, New York City, USA.

Cureus
|January 4, 2021
PubMed

Insights

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause heart damage, not just lung injury. This case highlights new-onset heart failure due to COVID-19 induced myocarditis in a young male patient.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily targets the lungs by binding to angiotensin-converting enzyme 2 (ACE-2) receptors.
  • ACE-2 receptors are also present in cardiac and vascular tissues, suggesting potential for multi-organ involvement beyond the respiratory system.
  • Coronavirus disease 2019 (COVID-19) typically presents with respiratory symptoms but can lead to diverse complications.

Observation:

  • A 40-year-old male presented with shortness of breath, a common COVID-19 symptom.
  • Further investigations revealed the patient developed new-onset heart failure.
  • The heart failure was diagnosed as secondary to COVID-19 induced myocarditis.

Findings:

  • The case demonstrates that SARS-CoV-2 can induce myocarditis, leading to acute heart failure.
  • This highlights the potential for cardiac complications in COVID-19 patients, even in younger individuals.
  • The binding of SARS-CoV-2 to ACE-2 receptors in the heart contributes to myocardial injury.

Implications:

  • This case underscores the importance of considering cardiac complications in COVID-19 patients presenting with respiratory or non-specific symptoms.
  • Early recognition and management of COVID-19 induced myocarditis are crucial for preventing severe heart failure.
  • Further research is warranted to understand the mechanisms and long-term cardiovascular consequences of SARS-CoV-2 infection.
Keywords:
covid 19covid and myocarditiscovid-induced myocarditisheart failure with reduced ejection fraction

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