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Gout in Pregnancy: A Rare Phenomenon
Kevin Pierre1, Noah F Gomez2, Catarina Canha3
1Neurosurgery, University of Florida College of Medicine, Gainesville, USA.
Cureus
|January 4, 2021
Summary
Gout is rare in pregnant women. This case report details successful management of acute gout flare and Haemophilus influenzae sepsis in pregnancy using colchicine and steroids, despite a subsequent miscarriage.
Area of Science:
- Rheumatology
- Obstetrics
- Infectious Disease
Background:
- Gout is uncommon in women of reproductive age due to estrogen's uricosuric effect.
- Gout during pregnancy is exceptionally rare, with limited case reports available.
- Estrogen's physiological uricosuric effect typically protects women of reproductive age from gout flares.
Observation:
- A 21-year-old pregnant woman (4 weeks gestation) presented with acute polyarticular gout.
- The condition was complicated by Haemophilus influenzae sepsis and hyperemesis gravidarum.
Findings:
- The gout flare was likely triggered by H. influenzae bacteremia, treated successfully with antibiotics.
- Acute gout flare in pregnancy was managed effectively with colchicine and intra-articular steroid injections.
Implications:
- This case highlights a successful therapeutic approach for managing acute gout flares in pregnant patients.
- It underscores the challenges and potential treatment strategies for gout during pregnancy, despite a reported miscarriage.
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