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Tissue Engineering of the Intestine in a Murine Model
Published on: December 1, 2012
Nutritional and pharmacological strategy in children with short bowel syndrome
Michael E Höllwarth1, Valeria Solari2
1Univ. Clinic of Pediatric and Adolescent Surgery, Medical University, Graz, Austria. michael.hoellwarth@medunigraz.at.
Abstract:
Short bowel syndrome in neonates is a severe and life-threatening disease after a major loss of small bowel with or without large bowel. Intestinal adaptation, by which the organism tries to restore digestive and absorptive capacities, is entirely dependent on stimulation of the active enterocytes by enteral nutrition. This review summarizes recent knowledge about the pathophysiologic consequences after the loss of different intestinal parts and outlines the options for enteral nutrition and pharmacological therapies to support the adaptation process.
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