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Clinical Profile, Risk-Factors, and Outcome of Rotaviral Diarrhea and Non-rotaviral Diarrhea Among Under-Five

Subal Kumar Pradhan1, Sumanta Panigrahi2, Pooja Sagar Padhi3

  • 1Department of Pediatrics, Sardar Vallabhbhai Patel Post Graduate Institute of Pediatrics (SVPPGIP) & SCB Medical College, Cuttack, Odisha, India. drsubal@Rediffmai.com.

Indian Journal of Pediatrics
|January 4, 2021
PubMed

Insights

Rotavirus diarrhea affects over a third of young children hospitalized in India. Younger children aged 6-23 months face higher risks of rotavirus infection, highlighting the need for targeted interventions.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Diarrheal diseases are a leading cause of childhood hospitalization globally.
  • Rotavirus is a primary pathogen responsible for severe gastroenteritis in infants and young children.

Purpose of the Study:

  • To determine the prevalence of rotavirus diarrhea among hospitalized children under five years of age.
  • To identify clinical and socio-demographic factors associated with rotavirus diarrhea.

Main Methods:

  • A prospective hospital-based study was conducted in Odisha, India, from April 2016 to July 2019.
  • Data on clinical and socio-demographic characteristics were collected from 1963 children.
  • Simple logistic regression was used to analyze factors associated with rotavirus diarrhea.

Main Results:

  • The prevalence of rotavirus diarrhea was 36.4% among the studied children.
  • Children aged 6-23 months had significantly higher odds of rotavirus diarrhea compared to older children (24-59 months).
  • Prevalence of malnutrition (wasting, stunting, underweight) was noted in children with rotavirus diarrhea.

Conclusions:

  • Diarrhea continues to be a significant reason for pediatric hospital admissions.
  • Further community-based research, including rotavirus genotyping, is recommended to inform prevention strategies.
Abstract

Keywords:
Clinical profileDiarrheaRisk factorsRotavirus

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