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Updated: Nov 23, 2025

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
COVID-19 myocarditis and long-term heart failure sequelae
Jing Liu1, Anita Deswal2, Umair Khalid3
1Section of Cardiology, Department of Medicine, Baylor College of Medicine.
Coronavirus disease 2019 (COVID-19) can cause myocarditis and long-term heart failure. Early diagnosis and treatment are crucial for managing cardiac dysfunction in COVID-19 patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic.
- Cardiac dysfunction and heart failure are common complications in COVID-19 patients.
- Myocardial involvement in COVID-19 requires careful evaluation.
Purpose of the Study:
- To provide a comprehensive review of COVID-19 myocarditis.
- To discuss the long-term heart failure sequelae associated with COVID-19.
- To explore diagnostic and therapeutic strategies for COVID-19-related cardiac dysfunction.
Main Methods:
- Review of existing literature on COVID-19 myocarditis.
- Analysis of clinical presentations and diagnostic findings.
- Evaluation of treatment strategies and outcomes.
Main Results:
- COVID-19 can lead to a spectrum of ventricular dysfunction, including myocarditis.
- Distinguishing myocarditis from other causes of cardiac dysfunction (e.g., cytokine storm, microvascular thrombosis) is challenging.
- Myocardial dysfunction in COVID-19 is associated with poor prognosis.
Conclusions:
- Timely diagnosis of COVID-19 myocarditis is essential, utilizing laboratory tests, echocardiography, cardiac MRI, and potentially endomyocardial biopsy.
- Management involves supportive care and targeted therapies.
- Further research is needed to determine the prevalence of COVID-19 myocarditis and refine diagnostic and treatment protocols.
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