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Sickle cell trait (SCT) can cause exertional collapse (ECAST), even sudden death. A 2019 summit addressed SCT policies, ECAST management, education, and research to improve safety for military personnel.

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Area of Science:

  • Sports Medicine
  • Hematology
  • Military Health

Background:

  • Sickle cell trait (SCT) is generally benign but linked to exertional events, including sudden death.
  • The term exercise collapse associated with SCT (ECAST) was established in 2011.
  • Recent ECAST deaths in military personnel highlighted the need for policy and guideline reevaluation.

Purpose of the Study:

  • To review and update Department of Defense policies regarding SCT screening.
  • To develop procedural instructions for SCT policy implementation.
  • To create clinical practice guidelines for ECAST management, establish an educational framework, and outline a research agenda.

Main Methods:

  • Convened a summit in October 2019 with experts from the Consortium for Health and Military Performance.
  • Reviewed existing service policies on SCT screening.
  • Focused on developing draft guidelines and procedural instructions for SCT and ECAST.

Main Results:

  • Identified critical areas for policy and guideline development related to SCT and ECAST.
  • Established a framework for education and research on SCT and ECAST within the military.
  • Initiated a comprehensive reevaluation of current practices and future needs.

Conclusions:

  • The 2019 summit provided a roadmap for improving the management and prevention of ECAST in military settings.
  • Addressing SCT and ECAST requires updated policies, clinical guidelines, education, and targeted research.
  • Proactive measures are essential to mitigate the risks associated with SCT during strenuous activity.