Summit on Exercise Collapse Associated with Sickle Cell Trait: Finding the "Way Ahead"

Area of Science:

• Sports Medicine
• Hematology
• Military Health

Background:

• Sickle cell trait (SCT) is generally benign but linked to exertional events, including sudden death.
• The term exercise collapse associated with SCT (ECAST) was established in 2011.
• Recent ECAST deaths in military personnel highlighted the need for policy and guideline reevaluation.

Purpose of the Study:

• To review and update Department of Defense policies regarding SCT screening.
• To develop procedural instructions for SCT policy implementation.
• To create clinical practice guidelines for ECAST management, establish an educational framework, and outline a research agenda.

Main Methods:

• Convened a summit in October 2019 with experts from the Consortium for Health and Military Performance.
• Reviewed existing service policies on SCT screening.
• Focused on developing draft guidelines and procedural instructions for SCT and ECAST.

Main Results:

• Identified critical areas for policy and guideline development related to SCT and ECAST.
• Established a framework for education and research on SCT and ECAST within the military.
• Initiated a comprehensive reevaluation of current practices and future needs.

Conclusions:

• The 2019 summit provided a roadmap for improving the management and prevention of ECAST in military settings.
• Addressing SCT and ECAST requires updated policies, clinical guidelines, education, and targeted research.
• Proactive measures are essential to mitigate the risks associated with SCT during strenuous activity.