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Priapism associated with trazodone therapy.

C C Carson1, R D Mino

  • 1Division of Urologic Surgery, Duke University Medical Center, Durham, North Carolina 27710.

The Journal of Urology
|February 1, 1988
PubMed
Summary
This summary is machine-generated.

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Priapism, a prolonged erection, can be difficult to treat when caused by medications. This study discusses two cases linked to trazodone therapy and reviews treatment options.

Area of Science:

  • Urology
  • Pharmacology
  • Sexual Medicine

Background:

  • Priapism is a medical emergency requiring prompt treatment.
  • Medication-induced priapism presents unique therapeutic challenges.
  • Trazodone is an antidepressant with known side effects, including priapism.

Observation:

  • Two distinct cases of priapism and prolonged erection were observed in patients undergoing trazodone therapy.
  • These events highlight a potential adverse effect of trazodone.

Findings:

  • Priapism associated with trazodone therapy can occur.
  • The literature review indicates trazodone as a potential cause of priapism.
  • Successful management strategies for trazodone-induced priapism require careful consideration.

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Implications:

  • Clinicians should be aware of the risk of priapism with trazodone use.
  • Early recognition and intervention are crucial for managing trazodone-induced priapism.
  • Further research into the mechanisms and optimal treatments for drug-induced priapism is warranted.