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Updated: Nov 23, 2025

Author Spotlight: Streamlining Cell Analysis with an Innovative Protocol for Studying Spiny Mouse Models
Published on: November 15, 2024
Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin
Janak Gaire1, Justin A Varholick2, Sabhya Rana3
1Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, 32611, USA.
Abstract:
The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.

