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Anaphylactic injury--a process of programmed regulation
Annals of Allergy
|October 1, 1977
Abstract:
Anaphylactic injury is a process of tissue destruction mediated by vasoactive amines secreted by basophils and/or mast cells. A cellular model is proposed involving the immunoregulatory properties of basophils, eosinophils and lymphocytes. The interaction of these cells speaks for programmed control mechanisms, the impairment of which leads to expression of anaphylaxis.