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Measuring Dengue Virus RNA in the Culture Supernatant of Infected Cells by Real-time Quantitative Polymerase Chain Reaction
Published on: November 1, 2018
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[Dengue economic impact in Paraguay].
Celia Martínez de Cuellar1, Dolores Lovera1, Oscar Merlo1
1Instituto de Medicina Tropical, Paraguay.
Summary
Dengue significantly impacts Paraguay
Area of Science:
- Public Health
- Epidemiology
- Health Economics
Background:
- Dengue outbreaks have recurrently impacted Paraguay since the late 20th century.
- High morbidity and mortality rates of dengue result in substantial global socio-economic consequences and strain healthcare systems.
Purpose of the Study:
- To quantify the economic cost and overall burden of dengue in Paraguay.
Main Methods:
- Estimated direct and indirect costs for both outpatient and hospitalized dengue cases.
- Calculated disability-adjusted life years (DALY) by summing years of life lost (YPLL) from premature mortality and years lost to disability (DVSP).
Main Results:
- The cost per ambulatory case was $52.5 USD, and per hospitalized patient was $300 USD.
- Total costs over four years reached $276,804.864 USD for ambulatory cases and $23,236.45 USD for hospitalized cases.
- Years of life lost (YPLL) were 18,469.7 per million inhabitants, with 185,835 years lost to disability (DVSP) and 32,676 DALYs per million inhabitants.
Conclusions:
- Dengue represents a significant economic burden on Paraguay's health sector and general economy.
- The study highlights the substantial financial and societal costs associated with dengue in the region.
