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Updated: Oct 3, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
[Salmonella Enteritidis meningitis in an infant. Case report and literature review]
Constanza Bay1, Macarena Jofré1, Daniela Kuzmanic2
1Programa de Formación en Pediatría, Departamento de Pediatría, Pontificia Universidad Católica de Chile, Santiago, Chile.
Insights
Salmonella Enteritidis meningitis is rare in infants but requires prompt diagnosis and treatment. This case highlights successful treatment with ceftriaxone and ciprofloxacin in an 11-month-old.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Salmonella spp meningitis is a rare but serious condition in children, particularly those under six months.
- The enteric subspecies, especially Salmonella Enteritidis, is the most common worldwide.
- High complication rates, including collections and abscesses, necessitate neuroimaging for all patients.
Observation:
- This report details the first case of Salmonella Enteritidis meningitis in Chile.
- The patient was an 11-month-old infant presenting with fever and focal epileptic seizures.
- Blood and cerebrospinal fluid cultures confirmed Salmonella Enteritidis infection.
Findings:
- The infant received a four-week treatment course comprising ceftriaxone and ciprofloxacin.
- The patient demonstrated a positive response to the prescribed antibiotic therapy.
- Antibiotic resistance, though infrequent, is a growing concern, particularly in developing nations.
Implications:
- This case underscores the importance of considering Salmonella Enteritidis in pediatric meningitis, even in regions where it's less common.
- Early diagnosis and appropriate antibiotic treatment, such as third-generation cephalosporins, are crucial for favorable outcomes.
- Continued surveillance for antibiotic resistance in Salmonella spp is essential for effective treatment strategies.
Abstract:
Salmonella spp meningitis is rare in pediatrics. However, it should be especially suspected in children younger than 6 months. The enteric subspecies is the most frequent worldwide, with the Enteritidis serovar being the most important. The complication rate is high, with collections and abscesses predominating. For this reason, neuroimaging is currently recommended for all patients. Even though management is not standardized, there is consensus that first line treatment should be with third generation cephalosporins. Antibiotic resistance is infrequent but increasing, mainly in underdeveloped countries. We present the first case reported in Chile of meningitis by Salmonella Enteritidis in an 11-month-old infant presenting with fever and focused epileptic crisis. Blood culture and cerebrospinal fluid culture were positive. The patient completed four weeks of treatment with ceftriaxone and ciprofloxacin with a good response.
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