Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Biphasic, refractory, and life-threatening anaphylactic reactions to iodinated contrast media: A 10-year retrospective analysis.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2025

Same author

Benign and Malignant Pediatric Liver Masses: Radiologic-Pathologic Update from the Pediatric LI-RADS Working Group.

Radiographics : a review publication of the Radiological Society of North America, Inc·2025

Same author

Imaging Manifestations of Alcohol Use-associated Disorders and Diseases.

Radiographics : a review publication of the Radiological Society of North America, Inc·2025

Same author

Is retirement a pain in the back? A 23-year population-based study on the impact of age and employment on spinal injections.

The neuroradiology journal·2025

Same author

Serum and Urine Gadolinium Reference Intervals in Patients With Normal Renal Function Following Gadobutrol Administration.

Investigative radiology·2025

Same author

Imaging Findings and Management Strategies for Liver Masses in Children with Predisposition Disorders: A Review by the Pediatric LI-RADS Group.

Radiographics : a review publication of the Radiological Society of North America, Inc·2024

Search research articles

Related Experiment Video

Updated: Nov 23, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Asymptomatic macrocephaly: to scan or not to scan.

Claire N Thomas¹, Amy B Kolbe², Larry A Binkovitz³

¹Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, USA.

Pediatric Radiology

|January 5, 2021

Summary

Head ultrasound (US) is a useful screening tool for infants with macrocephaly. This study found US effectively identifies significant pathology, helping to exclude serious conditions when results are normal.

Keywords:

Brain Head Infant Macrocephaly Macrocrania Ultrasound

More Related Videos

State of the Art Cranial Ultrasound Imaging in Neonates

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent

Published on: May 19, 2023

Related Experiment Videos

Last Updated: Nov 23, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

State of the Art Cranial Ultrasound Imaging in Neonates

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent

Author Spotlight: High-Resolution Imaging of Mouse Neonate Brains – A Micro-CT Protocol with Lugol's Solution Contrast Agent

Published on: May 19, 2023

Area of Science:

Pediatric Neurology
Diagnostic Imaging
Neonatal Care

Background:

Macrocephaly is common in infants, often benign (idiopathic or familial).
Distinguishing concerning macrocephaly from normal variation requires careful evaluation.
Identifying underlying pathology is crucial for timely intervention.

Purpose of the Study:

To assess the utility of head ultrasound (US) screening in asymptomatic infants with macrocephaly.
To identify clinical factors associated with significant US findings in this population.

Main Methods:

Retrospective review of 440 infants with macrocephaly undergoing head US over 20 years.
Data included demographics, head circumference, physician specialty, US, CT/MRI findings, and clinical course.
Analysis focused on identifying associations between clinical factors and significant US findings.

Main Results:

64% of US studies were normal; 31% had incidental findings.
Only 1.8% of infants had significant findings confirmed by CT/MRI (e.g., tumors, hydrocephalus).
Head circumference at birth was the only significant predictor of abnormal findings.

Conclusions:

Head ultrasound is a valuable initial diagnostic tool for infantile macrocephaly.
US can identify treatable causes and effectively rule out significant pathology when normal.
This imaging modality aids in clinical decision-making for asymptomatic infants.