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Published on: February 12, 2017
Reminiscence therapy-based care program relieves anxiety, depression, and improves quality of life in
1Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Objectives:
The study aimed to explore the effect of reminiscence therapy-based care program (RTCP) on anxiety, depression, quality of life (QoL), and survival profiles in post-operational non-small cell lung cancer (NSCLC) patients.
Methods:
In this randomized, controlled study, a total of 192 newly diagnosed post-operational NSCLC patients were randomly assigned to control care program (CCP) group (N = 96) or RTCP group (N = 96), and both groups experienced 12-month intervention and 36-month follow-up without intervention. Hospital Anxiety and Depression Scale (HADS) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) were evaluated at baseline (M0), month (M)3, M6, and M12.
Results:
Reduced HADS-anxiety score at M6 and M12, anxiety rate at M12, and anxiety severity at M6 and M12 were observed in RTCP group compared with CCP group. Additionally, HADS-depression score was decreased at M6 and M12, while both depression rate and severity were of no difference at each time point between two groups. Furthermore, QLQ-C30 global health status score at M6 and M12, QLQ-C30 functions score at M12 were increased, while QLQ-C30 symptoms score was of no difference at each time point in RTCP group compared with CCP group. Regarding survival profiles, Kaplan-Meier curves indicated that disease-free survival and overall survival were of no difference between two groups, further multivariate Cox's proportional hazard regression analysis also observed the same trends.
Conclusion:
RTCP effectively relieves anxiety and depression, improves QoL, but did not prolong survival, suggesting its value as a non-pharmacological approach for post-operational NSCLC management.
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