Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The patient journey for people with dementia and their carers in Peru: From first symptoms to diagnosis and treatment.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026
Same author

Barriers and facilitators to intracerebral haemorrhage platform trial recruitment: a survey of stroke clinicians.

Cerebrovascular diseases (Basel, Switzerland)·2026
Same author

Participants' experiences of living with cystic fibrosis related diabetes and using a hybrid closed-loop system to support self-management: qualitative study.

BMC endocrine disorders·2026
Same authorSame journal

World Stroke Organization (WSO) rehabilitation certification program.

International journal of stroke : official journal of the International Stroke Society·2026
Same author

Interferon-α as a precision medicine tool in Sjögren's disease: a cohort and experimental medicine study.

The Lancet. Rheumatology·2026
Same author

A large dataset of brain imaging linked to health systems data: curation and access to a whole system national cohort from NHS Scotland.

GigaScience·2026

Related Experiment Video

Updated: Nov 22, 2025

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
09:10

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

Published on: February 22, 2020

8.9K

Predicting specific abilities after disabling stroke: Development and validation of prognostic models.

Akila Visvanathan1, Catriona Graham2, Martin Dennis1

  • 1Centre for Clinical Brain Sciences, Chancellor's Building, The University of Edinburgh, Edinburgh, UK.

International Journal of Stroke : Official Journal of the International Stroke Society
|January 6, 2021
PubMed
Summary

New statistical models predict stroke recovery outcomes, including walking and talking abilities, six months post-stroke. These models aid patient preparation and treatment decisions for better stroke rehabilitation.

Keywords:
Prognostic modelsdecision-makingdisabilitypredictionprognosisstroke

More Related Videos

Computerized Adaptive Testing System of Functional Assessment of Stroke
05:21

Computerized Adaptive Testing System of Functional Assessment of Stroke

Published on: January 7, 2019

6.1K
Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

11.8K

Related Experiment Videos

Last Updated: Nov 22, 2025

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke
09:10

Determining the Functional Status of the Corticospinal Tract Within One Week of Stroke

Published on: February 22, 2020

8.9K
Computerized Adaptive Testing System of Functional Assessment of Stroke
05:21

Computerized Adaptive Testing System of Functional Assessment of Stroke

Published on: January 7, 2019

6.1K
Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke
08:01

Compensatory Limb Use and Behavioral Assessment of Motor Skill Learning Following Sensorimotor Cortex Injury in a Mouse Model of Ischemic Stroke

Published on: July 10, 2014

11.8K

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Biostatistics

Background:

  • Predicting functional abilities after stroke is crucial for patient preparedness and treatment planning.
  • Specific abilities like walking and talking post-stroke significantly impact quality of life.

Purpose of the Study:

  • To develop and validate statistical models for predicting six key abilities six months after a disabling stroke.
  • To assess the performance of these predictive models in an independent patient cohort.

Main Methods:

  • Developed multivariable logistic regression models using data from 13,117 stroke patients across seven trials.
  • Included prediction of independence, walking, talking, normal eating, mental well-being, and living at home.
  • Validated models in an independent cohort of 403 patients, assessing discrimination and calibration.

Main Results:

  • All six models demonstrated good discrimination in external validation (AUC 0.78-0.84).
  • Four models (walking, eating, mental well-being, living at home) showed good calibration.
  • Model sensitivities ranged from 45.0% to 97.9%, and specificities from 21.6% to 96.5%.

Conclusions:

  • Successfully developed and validated statistical models to predict specific functional abilities post-stroke.
  • These models show reasonable performance in an independent cohort of disabling stroke patients.
  • Further evaluation is needed to integrate these models into clinical decision-making for stroke treatments.