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Massive Tibial Bone Regeneration with Autologous Peripheral Blood Stem Cells using Ilizarov Bone Transport: A Case

K Y Saw¹, R Gill¹, T C Low¹

¹Department of Orthopaedic Surgery, Kuala Lumpur Sports Medicine Centre, Kuala Lumpur, Malaysia.

Malaysian Orthopaedic Journal

|January 6, 2021

Abstract:

This is a case report of a Gustilo-Anderson Type IIIB comminuted open right tibial fracture with massive bone loss, complicated by methicillin-resistant Staphylococus aureus (MRSA) infection. Non-viable and contaminated bony fragments were removed and infected bone resected. Soft tissue coverage and antibiotics were effective against the MRSA infection. A unifocal bone transport with the Ilizarov method regenerated 13cm of the missing tibia. Autologous peripheral blood stem cells (PBSC) injections into the osteogenesis site boosted bone regeneration and consolidation with a shortened Bone Healing index (BHI) of 23 days/cm.

Keywords:

Bone Healing index Ilizarov bone regeneration massive bone loss peripheral blood stem cells

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