Related Experiment Video
Updated: Nov 22, 2025

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
COVID-19: Implications for bipolar disorder clinical care and research
Siqi Xue1, M Ishrat Husain1,2, Abigail Ortiz1,2
1Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Abstract:
The COVID-19 pandemic has posed significant challenges to health care globally, and individuals with bipolar disorder are likely disproportionally affected. Based on review of literature and collective clinical experience, we discuss that without special intervention, individuals with bipolar disorder will experience poorer physical and mental health outcomes due to interplay of patient, provider and societal factors. Some risk factors associated with bipolar disorder, including irregular social rhythms, risk-taking behaviours, substantial medical comorbidities, and prevalent substance use, may be compounded by lockdowns, social isolation and decrease in preventive and maintenance care. We further discuss implications for clinical research of bipolar disorders during the pandemic. Finally, we propose mitigation strategies on working with individuals with bipolar disorder in a clinical and research context, focusing on digital medicine strategies to improve quality of and accessibility to service.
More Related Videos
Related Concept Videos
Bipolar Disorder
Mania and Antimanic Drugs: Overview
Depression: Overview
Psychosis: Goals of Pharmacotherapy
Diagnostic and Statistical Manual of Mental Disorders (DSM)
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

