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Published on: August 18, 2023
The prevalence of obstructive sleep apnea in interstitial lung disease: a systematic review and meta-analysis
Yang Cheng1, Yan Wang2, Li Dai2
1Department of Respiratory and Critical Care Medicine, Beijing Jishuitan Hospital, The Fourth Medical College of Peking University, No. 31, Xinjiekou East Street, Beijing, 100035, China. chengyang0323@outlook.com.
Purpose:
To evaluate the overall prevalence of obstructive sleep apnea (OSA) in interstitial lung disease (ILD).
Methods:
We performed a systematic search of the academic literature while adhering to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines on four scientific databases including EMBASE, CENTRAL, Scopus, and MEDLINE. We performed a meta-analysis to evaluate the prevalence and severity of OSA. Severity was defined by apnea-hypopnea index (AHI) as mild (AHI ≥ 5 to < 15/h), moderate (AHI ≥ 15 to < 30/h), and severe (AHI ≥ 30/h).
Results:
From 1397 studies, we found 10 eligible studies with 569 patients with ILD (mean age: 65.3 ± 6.0 years). Among these patients, 332 (61%) suffered from OSA with 32% categorized as mild, 17% moderate, and 9% severe. CONCLUSION: This systematic review and meta-analysis provides preliminary evidence regarding the high prevalence of OSA in ILD.
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