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Metal-Organic Framework and Hydrogel Based Strategy as a Universal First-Aid Treatment of Three Different Typical
Ruolei Li1,2, Fei Cao1, Yutong Chen1
1The National Engineering Research Center for Bioengineering Drugs and the Technologies: Institition of Translational Medicine, Nanchang University, Nanchang, Jiangxi 330088, China.
Abstract:
Snake bite envenoming is a worldwide problem which affects the health and safety of the public. The classical antivenom methods are difficult to be used immediately and accurately. Based on this situation, a new metal-organic framework and hydrogel based first-aid treatment was first set up in this study as a facile, economic, effective, and universal alternative strategy. According to the subsequent in vitro and in vivo experiments, this dual effective (block and absorption) strategy was proven to be useful in dealing with three different representative snake venoms (Bungarus fasciatus, Protobothrops mucrosquamatus, and cobra venom).
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