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Modular Assembly of Biomaterials Using Polyphenols as Building Blocks.
Junling Guo1,2, Tomoya Suma3, Joseph J Richardson4
1Department of Biomass Chemistry and Engineering, Sichuan University, Chengdu 610065, China.
ACS Biomaterials Science & Engineering
|January 6, 2021
Summary
Polyphenols offer a versatile platform for creating advanced biomaterials like particles, films, and gels. These natural compounds enable the development of innovative materials for applications such as drug delivery and theranostics.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Nanotechnology
Background:
- Polyphenols are natural, abundant, biocompatible, and biodegradable building blocks.
- Their assembly mechanisms allow for diverse material properties and stimuli responses.
- Modular synthesis routes facilitate the creation of various biomaterials.
Purpose of the Study:
- To review recent advancements in biomaterials engineering utilizing polyphenols.
- To categorize polyphenol-based biomaterials into particles, films, and gels.
- To overview their assembly, functions, and applications in biological systems.
Main Methods:
- Literature review of recent progress in polyphenol biomaterials.
- Categorization based on material form (particles, films, gels).
- Analysis of synthesis, assembly, and biological applications.
Main Results:
- Polyphenol-based biomaterials can be engineered across various length scales.
- Diverse physical/chemical properties and stimuli responses are achievable.
- Applications include drug delivery and theranostics.
Conclusions:
- Polyphenols provide a powerful and adaptable platform for biomaterial design.
- The reviewed materials demonstrate significant potential for biomedical applications.
- Further research into polyphenol biomaterials will drive innovation in drug delivery and theranostics.
