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Updated: Nov 22, 2025

2-Methacryloyloxyethyl Phosphorylcholine Polymer Treatment of Complete Dentures to Inhibit Denture Plaque Deposition
Published on: December 26, 2016
Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce C. albicans Biofouling
Anna Waterhouse1, Daniel C Leslie1, Kayla Lightbown1
1Wyss Institute for Biologically Inspired Engineering at Harvard University, 3 Blackfan Circle, Boston, Massachusetts 02115, United States.
Abstract:
Localized infections caused by biofilm formation on dentures pose a serious health risk for patients, especially the elderly, as they can lead to complications such as pneumonia. Daily enzymatic denture cleaners do not fully prevent biofilm formation on dentures. Here we developed a rapid coating process to apply a liquid repellent surface to dentures in ∼5 min and demonstrated a significant 225-fold reduction of Candida albicans adhesion over 6 days, compared to uncoated dentures. This rapid coating process could be applied to dentures and other dental devices chair-side and allow the research community to quickly and easily generate ominphobic surfaces.

