Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nonconjugative plasmids encoding sulfanilamide resistance.

S Mitsuhashi, K Inoue, M Inoue

    Antimicrobial Agents and Chemotherapy
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Ion channels on synaptic vesicle membranes studied by planar lipid bilayer method.

    Biophysical journal·1992
    Same author

    Extracellular matrix formation in piecemeal necrosis: immunoelectron microscopic study.

    Liver·1992
    Same author

    Roles of Ca2+ influx through ATP-activated channels in catecholamine release from pheochromocytoma PC12 cells.

    Journal of neurophysiology·1992
    Same author

    Establishment of a folliculo-stellate-like cell line from a murine thyrotropic pituitary tumor.

    Endocrinology·1992
    Same author

    An extract of Gymnema sylvestre leaves and purified gymnemic acid inhibits glucose-stimulated gastric inhibitory peptide secretion in rats.

    The Journal of nutrition·1992
    Same author

    [Selection of methods for diagnosis and treatment of pancreatic cancer].

    Gan to kagaku ryoho. Cancer & chemotherapy·1992
    Same journal

    Addressing therapeutic options for KPC-3-producing ST307-<i>Klebsiella pneumoniae</i>: insights from <i>in vitro</i> evolution and mutant prevention strategies.

    Antimicrobial agents and chemotherapy·2026
    Same journal

    Indole-based hybrids target both asexual parasites and gametocytes of <i>Plasmodium falciparum</i> and synergize with lumefantrine.

    Antimicrobial agents and chemotherapy·2026
    Same journal

    Lineage-specific loss of the type VI secretion system in <i>Acinetobacter baumannii</i> ST19 is associated with reduced accessory genome content.

    Antimicrobial agents and chemotherapy·2026
    Same journal

    Genomic diversity and topical antimicrobial resistance in <i>Staphylococcus aureus</i> from clinical and carriage populations in the New York-New Jersey region.

    Antimicrobial agents and chemotherapy·2026
    Same journal

    Characterization of GUA-1, a chromosomally encoded ESBL from <i>Pseudomonas guariconensis-like</i>.

    Antimicrobial agents and chemotherapy·2026
    Same journal

    A monoclonal antibody targeting OXA23 restores carbapenem susceptibility in global epidemic carbapenem-resistant <i>Acinetobacter baumannii</i>.

    Antimicrobial agents and chemotherapy·2026
    See all related articles

    High-frequency sulfanilamide resistance in Shigella and E. coli is linked to nonconjugative plasmids. These plasmids are compatible with standard types and range from 3.5 to 3.9 megadaltons in size.

    Area of Science:

    • Microbiology
    • Molecular Biology
    • Genetics

    Background:

    • Sulfanilamide resistance is a growing concern in bacterial pathogens.
    • Plasmids are key vectors for antibiotic resistance gene dissemination.

    Purpose of the Study:

    • To investigate the genetic basis of sulfanilamide resistance in Shigella and Escherichia coli.
    • To characterize the plasmids responsible for sulfanilamide resistance.

    Main Methods:

    • Isolation and characterization of sulfanilamide-resistant Shigella and E. coli strains.
    • Plasmid compatibility testing using standard reference plasmids.
    • Determination of plasmid size using electron microscopy.

    Main Results:

    • Nonconjugative plasmids encoding sulfanilamide resistance were frequently observed.

    Related Experiment Videos

  • These sulfanilamide resistance plasmids were compatible with standard plasmids.
  • Plasmid sizes ranged from 3.5 to 3.9 megadaltons.

    • Conclusions:

    • Nonconjugative plasmids play a significant role in the spread of sulfanilamide resistance in Shigella and E. coli.
    • The characterized plasmids represent a potential mechanism for resistance transfer.