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Common bile duct calculi: updated experience with dissolution with methyl tertiary butyl ether
J C Brandon1, S K Teplick, P H Haskin
1Department of Diagnostic Radiology, Hahnemann University Hospital, Philadelphia, PA 19102.
Radiology
|March 1, 1988
Summary
Methyl tertiary butyl ether (MTBE) effectively dissolves common bile duct stones, but its use is time-consuming and has odor challenges. This study evaluated MTBE
Area of Science:
- Gastroenterology
- Interventional Radiology
- Hepatobiliary Surgery
Background:
- Common bile duct (CBD) stones are a frequent clinical problem.
- Percutaneous dissolution offers a minimally invasive treatment option.
Purpose of the Study:
- To evaluate the effectiveness and limitations of methyl tertiary butyl ether (MTBE) for CBD stone dissolution.
- To report on a larger patient series than previously documented.
Main Methods:
- Ten patients with 13 biliary calculi were treated with percutaneous MTBE perfusion.
- MTBE, an experimental cholesterol solvent, was used for stone dissolution.
Main Results:
- Complete dissolution occurred in 3 of 13 stones within 30 minutes.
- Seven stones were reduced in size, and three were unaffected.
- All remaining stones were basket-extracted, except one requiring surgery.
Conclusions:
- MTBE perfusion is an effective technique for managing CBD calculi.
- Physicians must consider the time commitment and odor control challenges associated with MTBE use.