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Asthma and COVID-19: a systematic review
Natália F Mendes1,2, Carlos P Jara1,2, Eli Mansour3
1School of Nursing, State University of Campinas, Campinas, Brazil.
Asthma is not a significant risk factor for severe coronavirus disease-19 (COVID-19). This study found asthma reported in only 1.6% of COVID-19 patients, despite its 4.4% global prevalence.
Area of Science:
- Pulmonology
- Infectious Diseases
- Epidemiology
Background:
- Severe COVID-19 causes respiratory distress due to lung inflammation and hypoxia.
- Asthma has been investigated as a potential risk factor for severe COVID-19, but evidence remains inconclusive.
Purpose of the Study:
- To systematically review the literature on COVID-19 and asthma comorbidities.
- To determine if asthma is a significant premorbid condition associated with COVID-19 severity.
Main Methods:
- A systematic review of 372 articles published from December 2019 to June 2020.
- Analysis of underlying diseases in 161,271 COVID-19 patients.
Main Results:
- Asthma was reported in only 1.6% (2623 patients) of the analyzed COVID-19 cases.
- This prevalence is significantly lower than the global asthma prevalence of 4.4%.
Conclusions:
- Asthma does not appear to be a significant premorbid condition contributing to COVID-19 development.
- Potential underreporting or mischaracterization of asthma comorbidities in COVID-19 patients by clinicians and researchers is suggested.
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