Related Experiment Video
Updated: Nov 22, 2025

Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses
Published on: November 16, 2016
mSphere of Influence: the Complexity of Interferon Gamma-Mediated Pathogen Control
1Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA bryand@mit.edu.
Abstract:
Bryan D. Bryson works in the field of biological engineering with a specific interest in host-mycobacterium interactions. In this mSphere of Influence article, he reflects on how "IRG1 and inducible nitric oxide synthase act redundantly with other interferon-gamma-induced factors to restrict intracellular replication of Legionella pneumophila" by Price and colleagues (J. V. Price, D. Russo, D. X. Ji, R. A. Chavez, et al., mBio 10:e02629-19, 2019, https://doi.org/10.1128/mBio.02629-19) made an impact on him by reinforcing the complexity of intracellular pathogen control.
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