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Updated: Nov 22, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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Prostate cancer and sexual consequences among men who have sex with men

Patrick J Martin-Tuite1, Alan W Shindel2

  • 1Department of Urology, University of California San Francisco, San Francisco, CA, 94143-0738, USA.

International Journal of Impotence Research
|January 7, 2021
PubMed

Insights

Prostate cancer treatments cause sexual side effects impacting men who have sex with men (MSM). This review details their unique challenges, adaptations, and the need for better support for MSM prostate cancer survivors.

Area of Science:

  • Oncology
  • Sexual Health
  • Men's Health

Background:

  • Prostate cancer and its treatments often result in sexual dysfunction, affecting identity and relationships.
  • Sexual consequences of prostate cancer treatment can differ for men who have sex with men (MSM) compared to heterosexual men.
  • Lower screening rates for prostate cancer are documented in the MSM population, though prevalence data is unclear.

Purpose of the Study:

  • To review the literature from the past two decades on how men who have sex with men (MSM) are affected by and adapt to prostate cancer treatment.
  • To explore the unique sexual and psychological ramifications for MSM undergoing prostate cancer treatment.
  • To provide recommendations for improved care of MSM with prostate cancer.

Main Methods:

  • Systematic review of literature published over the last 20 years.
  • Analysis of studies focusing on the experiences of men who have sex with men (MSM) undergoing prostate cancer treatment.
  • Synthesis of evidence regarding sexual function, psychological impact, and coping strategies.

Main Results:

  • Prostate cancer treatment impacts urinary, bowel, and sexual function in both MSM and heterosexual men, with potentially different ramifications for MSM.
  • MSM with prostate cancer often experience a lack of support from medical professionals and sometimes their communities.
  • Many MSM survivors develop coping strategies and modify sexual practices to manage treatment side effects.

Conclusions:

  • Men who have sex with men (MSM) face distinct challenges related to sexual health after prostate cancer treatment.
  • Addressing the unique needs and support gaps for MSM prostate cancer survivors is crucial for their sexual wellness.
  • Insights from MSM survivors can inform better sexual health strategies for all prostate cancer survivors.

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