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Updated: Nov 22, 2025

Assessment of the Metabolic Effects of Isocaloric 2:1 Intermittent Fasting in Mice
Published on: November 27, 2019
Fasting and fasting-mimicking diets for chemotherapy augmentation
1Longevity Institute, School of Gerontology, and Department of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA. brandhor@usc.edu.
Prolonged fasting and fasting-mimicking diets show promise in cancer care. These dietary strategies may improve treatment outcomes and survival rates for cancer patients and survivors.
Area of Science:
- Oncology
- Nutrition Science
- Gerontology
Background:
- Aging populations face increased chronic disease risk, including cancer.
- Lifestyle factors like diet significantly influence cancer development and progression.
- Improved cancer survival necessitates strategies for treatment completion and recovery.
Purpose of the Study:
- To review the efficacy of fasting and fasting-mimicking diets in cancer treatment.
- To explore their potential to enhance patient outcomes and survival.
Main Methods:
- Review of preclinical studies in rodent models.
- Analysis of emerging clinical trial data in cancer patients.
Main Results:
- Preclinical research indicates strong support for fasting interventions.
- Early clinical trials suggest encouraging results for cancer patients and survivors.
Conclusions:
- Fasting and fasting-mimicking diets represent a promising adjunctive approach in cancer therapy.
- Further clinical research is warranted to optimize these dietary interventions for cancer care.
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