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Pruritus Intensity Scales across Europe: a prospective validation study.

M Storck1, S Sandmann1, P Bruland1,2

  • 1Institute of Medical Informatics, University of Münster, Münster, Germany.

Journal of the European Academy of Dermatology and Venereology : JEADV
|January 7, 2021
PubMed

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Summary
This summary is machine-generated.

Validated itch intensity scales, including the numerical rating scale and visual analogue scale (VAS), are reliable tools for assessing chronic pruritus across multiple European languages and various skin conditions. VAS worst demonstrated the best reproducibility.

Area of Science:

  • Dermatology
  • Clinical Assessment
  • Patient-Reported Outcomes

Background:

  • Chronic pruritus (CP) assessment requires validated patient-reported outcome tools.
  • Existing itch intensity scales have limitations due to small cohorts and single-language validation.

Purpose of the Study:

  • To validate numerical rating scale (NRS), verbal rating scale (VRS), and visual analogue scale (VAS) for worst and average pruritus intensity.
  • To assess these scales across multiple European languages and diverse pruritic dermatoses.

Main Methods:

  • Professional translation and digitization of scales into a tablet application.
  • Validation conducted in dermatology clinics across Austria, France, Germany, Italy, Poland, Russia, Spain, Switzerland, and Turkey.
  • Inclusion of 547 patients with conditions like contact dermatitis, chronic nodular prurigo, psoriasis, lichen planus, and cutaneous T-cell lymphoma.

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Main Results:

  • Scales demonstrated high reproducibility and inter-correlations.
  • Correlation with Dermatology Life Quality Index varied from weak to strong across countries and dermatoses, with exceptions noted.
  • Visual analogue scale for worst pruritus (VAS worst) showed excellent reproducibility and consistency.

Conclusions:

  • NRS, VRS, and VAS are valid instruments for assessing pruritus intensity in German, French, Italian, Polish, Russian, Spanish, and Turkish.
  • These scales exhibit good reproducibility and internal consistency for various pruritic dermatoses.
  • VAS worst is identified as the most reproducible and consistent measurement tool across all evaluated countries.