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Related Experiment Video

Updated: Nov 22, 2025

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Efficacy of acupuncture for sciatica: study protocol for a randomized controlled pilot trial.

Fang-Ting Yu1,2, Guang-Xia Ni3, Guo-Wei Cai4

  • 1International Acupuncture and Moxibustion Innovation Institute, Beijing University of Chinese Medicine, Beijing, 100029, China.

Trials
|January 8, 2021
PubMed
Summary
This summary is machine-generated.

This pilot study explores acupuncture for sciatica caused by lumbar disc herniation. It compares disease-affected meridians, non-affected meridians, and sham acupuncture to find the best treatment strategy.

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Area of Science:

  • Integrative and Complementary Medicine
  • Neurology
  • Pain Management

Background:

  • Acupuncture is frequently used for pain, but its effectiveness for sciatica lacks robust evidence.
  • Sciatica resulting from lumbar disc herniation is a common condition requiring effective treatment.
  • This study addresses the need for evidence on acupuncture's efficacy in treating sciatica.

Purpose of the Study:

  • To investigate the feasibility and efficacy of acupuncture for sciatica due to lumbar disc herniation.
  • To compare different acupoint selection strategies: disease-affected meridians (DAM) versus non-affected meridians (NAM).
  • To establish an optimal acupuncture strategy and inform the design of future large-scale studies.

Main Methods:

  • A multicenter, three-arm, patient-assessor-blinded randomized controlled pilot trial.
  • Ninety patients with sciatica were randomized into DAM, NAM, and sham acupuncture (SA) groups (1:1:1 ratio).
  • A 4-week treatment with a 22-week follow-up, measuring leg pain intensity (VAS) as the primary outcome.

Main Results:

  • The study is a pilot trial designed to assess feasibility and efficacy.
  • Primary outcome is the change in leg pain intensity (VAS) from baseline to week 4.
  • Secondary outcomes include functional status, back pain, and quality of life, with adverse events recorded.

Conclusions:

  • Results are expected to guide the selection of an optimal acupuncture strategy for sciatica.
  • This pilot study will inform the design and power calculation for a larger, definitive trial.
  • Findings will contribute to evidence-based acupuncture practice for lumbar disc herniation-induced sciatica.