Pericardial effusion in patients with COVID-19: case series

François Sauer1, Charlotte Dagrenat1, Philippe Couppie1

  • 1Division of Cardiovascular Medicine, Centre Hospitalier de Haguenau, 64 Avenue du Professeur Leriche, Haguenau, Alsace 67500, France.

Insights

Three patients with COVID-19 developed pericarditis, with two also experiencing myocarditis. Early colchicine treatment led to rapid improvement, highlighting the need for increased cardiologist awareness of these cardiac complications.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Cardiac Imaging

Background:

  • The global spread of SARS-coronavirus-2 (COVID-19) has presented numerous public health challenges.
  • Cardiac manifestations of COVID-19, including pericarditis and myocarditis, require further investigation.

Observation:

  • Three adult patients (ages 51-84) presented with COVID-19-related pericarditis.
  • Two patients also exhibited signs of myocarditis, with one case progressing to cardiac tamponade.
  • Diagnostic methods included chest CT scans, SARS-CoV-2 swabs, and pericardial fluid PCR.

Findings:

  • COVID-19 can lead to pericardial effusions, ranging from minimal to cardiac tamponade.
  • Myopericarditis is a recognized complication of COVID-19 infection.
  • Colchicine treatment demonstrated rapid clinical improvement in affected patients.

Implications:

  • Cardiologists should maintain a high index of suspicion for COVID-19-related pericarditis and myopericarditis.
  • Monitoring troponin kinetics and utilizing echocardiography can aid in early diagnosis.
  • Prompt recognition and treatment of these cardiac conditions are crucial for patient outcomes.
Abstract

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