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Related Experiment Video

Updated: Nov 22, 2025

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
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Cholera dynamics: lessons from an epidemic.

Deepak Balasubramanian1,2, Sebastian Murcia1,2, C Brandon Ogbunugafor3

  • 1National Center for Integrated Coastal Research, University of Central Florida, Orlando FL 32816, USA.

Journal of Medical Microbiology
|January 8, 2021
PubMed
Summary
This summary is machine-generated.

Cholera outbreaks in Latin America, driven by socioeconomic, political, and ecological factors, emerged in 1991 and largely disappeared by 1999. Lessons learned from this epidemic inform future cholera management in non-endemic regions.

Keywords:
Latin AmericaPeruVibrio choleraebackcastingcholeraepidemicpandemicspublic health

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Public Health

Background:

  • Cholera, caused by Vibrio cholerae O1, is a severe diarrheal disease with significant global mortality.
  • South America experienced a major cholera epidemic from 1991 to 1999 after a long absence.

Purpose of the Study:

  • To analyze the factors contributing to the emergence, spread, and disappearance of cholera in Latin America.
  • To identify lessons for future cholera outbreak management in non-endemic areas.

Main Methods:

  • Review of documented progression of the cholera epidemic in Latin America.
  • Analysis of socioeconomic, political, and ecological factors influencing cholera dynamics.
  • Evaluation of implemented control measures and their impact.

Main Results:

  • Cholera rapidly spread across Latin America following its reintroduction in 1991, causing millions of cases.
  • The epidemic's course was significantly altered by implemented public health interventions.
  • Cholera virtually disappeared from the continent by 1999.

Conclusions:

  • The Latin American cholera epidemic serves as a model for understanding disease dynamics.
  • Socioeconomic, political, and ecological factors are crucial in cholera emergence and spread.
  • Effective cholera management strategies can be developed for non-endemic areas based on this experience.