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Bioinformatics resources for SARS-CoV-2 discovery and surveillance
Briefings in Bioinformatics
|January 8, 2021
Summary
Bioinformatics pipelines and next-generation sequencing (NGS) rapidly identified SARS-CoV-2. These tools are crucial for global genomic surveillance, tracking the virus
Area of Science:
- Genomic surveillance
- Bioinformatics
- Virology
Background:
- The novel coronavirus (SARS-CoV-2) outbreak in Wuhan, China, was rapidly identified in early January 2020.
- Next-generation sequencing (NGS) and bioinformatics pipelines were instrumental in the initial virus discovery.
- These technologies are now vital for global genomic surveillance of SARS-CoV-2.
Discussion:
- This review summarizes bioinformatics resources essential for SARS-CoV-2 discovery and surveillance.
- It evaluates the strengths and weaknesses of current bioinformatics tools for viral genomics.
- Key areas requiring further technical development in bioinformatics are highlighted.
Key Insights:
- NGS and bioinformatics enable real-time tracking of SARS-CoV-2 spread, evolution, and variation globally.
- Effective bioinformatics resources are critical for understanding viral pandemics.
- The review identifies specific needs for advancing bioinformatics in infectious disease research.
Outlook:
- Improvements in bioinformatics will enhance the prevention and control of the COVID-19 pandemic.
- Advancements are crucial for preparedness against future infectious disease outbreaks.
- Developing robust bioinformatics pipelines is essential for global health security.
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