Related Experiment Video

Updated: Nov 22, 2025

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus
10:49

Assays for the Specific Growth Rate and Cell-binding Ability of Rotavirus

Published on: January 28, 2019

9.1K

Rotavirus Gastroenteritis Hospitalizations Among Under-Five Children in Bhubaneswar, Odisha, India

Prasantajyoti Mohanty1, Dilesh Kumar2, Asit Mansingh1

  • 1Rotavirus Vaccine Impact Assessment Study (RVIS), Jagannath Hospital, Bhubaneswar, Odisha, India.

Indian Journal of Pediatrics
|January 8, 2021
PubMed

Insights

Rotavirus gastroenteritis in children under five peaked from November to February in Odisha. The most common strains were G3P[8] and G1P[8], often causing severe dehydration.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Vaccinology

Background:

  • Rotavirus is a leading cause of severe diarrheal disease in young children globally.
  • Understanding local rotavirus epidemiology is crucial for vaccine efficacy assessment and public health strategies.

Observation:

  • A study in Bhubaneswar, Odisha, analyzed 1213 stool samples from children under five with acute gastroenteritis (AGE) between 2016 and 2019.
  • Rotavirus was detected in 36.9% of samples, predominantly in children aged 6 months to 2 years.

Findings:

  • Rotavirus gastroenteritis peaked from November to February.
  • Severe or very severe dehydration was observed in 92.6% of rotavirus cases.
  • The most prevalent rotavirus genotypes were G3P[8] (46%) and G1P[8] (19%).

Implications:

  • This data provides a clinical profile of rotavirus AGE in a vaccine-introduced area of Odisha.
  • Findings aid in documenting disease epidemiology and evaluating rotavirus vaccine performance in the region.
Abstract

Keywords:
Childhood diarrheaGenotypesIndiaOdishaPost-vaccination burdenRotavirus gastroenteritisSurveillance

More Related Videos

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR15:16

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Published on: July 22, 2012

17.5K
Swab Sampling Method for the Detection of Human Norovirus on Surfaces10:03

Swab Sampling Method for the Detection of Human Norovirus on Surfaces

Published on: February 6, 2017

20.0K

Related Concept Videos

Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.1K
Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
914
Esophageal Strictures-II: Clinical Features and Management01:26

Esophageal Strictures-II: Clinical Features and Management

Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
262
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
818
Pathophysiology of Vomiting01:22

Pathophysiology of Vomiting

Vomiting is a complex physiological response to expel harmful or irritating substances from the body. It's a defensive mechanism triggered by stimuli like poisons, microbial toxins, cytotoxic drugs, and mechanical abdominal distension. The process is centrally coordinated by the vomiting (or emetic) center located in the medulla of the brainstem. This area, rich in muscarinic M1, histamine H1, neurokinin 1 (NK1), and serotonin 5-HT3 receptors, coordinates the act of vomiting through...
2.0K
Drugs for Treatment of Diarrhea-Predominant IBS01:17

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
433