Introducing the 24-2C Visual Field Test in Neuro-Ophthalmology

Area of Science:

• Ophthalmology
• Neuro-ophthalmology
• Visual field testing

Background:

• The Humphrey 24-2C visual field test is a modification of the standard 24-2 test.
• It includes 10 additional test points within the central 10° of vision.
• This enhancement aims to improve the detection of central visual field defects.

Purpose of the Study:

• To compare the diagnostic capabilities of the Humphrey 24-2C visual field test against the standard Humphrey 10-2 visual field test.
• To evaluate the ability of the 24-2C test to detect central visual field defects in neuro-ophthalmology patients.

Main Methods:

• Twenty-five neuro-ophthalmology patients (42 eyes) underwent both 24-2C and 10-2 visual field testing.
• The number of flagged total deviation (TD) and pattern deviation (PD) points in the central 10° were compared between the two tests.
• Statistical significance was assessed at P < 5%, P < 2%, and P < 1% levels.

Main Results:

• No significant difference was found in flagged TD and PD points between the 24-2C's added points and the 10-2 test results across all significance levels.
• Analysis by diagnosis (optic neuritis, ischemic optic neuropathy, optic atrophy, no disease) showed no significant difference in flagged TD points.
• The 24-2C test successfully identified visual field defects and spared central vision, demonstrating comparable diagnostic value to the 10-2 test.

Conclusions:

• The Humphrey 24-2C test detects central visual field loss comparable to the 10-2 test.
• The 24-2C test shows potential as a hybrid strategy, combining elements of the 24-2 and 10-2 tests for comprehensive visual field evaluation.