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Related Concept Videos

Factors Affecting Solubility04:01

Factors Affecting Solubility

35.8K
Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
35.8K
Solubility03:00

Solubility

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Solution, Solubility, and Solubility Equilibrium
A solution is a homogeneous mixture composed of a solvent, the major component, and a solute, the minor component. The physical state of a solution—solid, liquid, or gas—is typically the same as that of the solvent. Solute concentrations are often described with qualitative terms such as dilute (of relatively low concentration) and concentrated (of relatively high concentration).
In a solution, the solute particles (molecules,...
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Extraction: Advanced Methods00:56

Extraction: Advanced Methods

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Solvents01:12

Solvents

68.8K
A solvent is a substance, most often a liquid, that can dissolve other substances. Here, the substance being dissolved is called a solute. When a solvent and a solute combine, they form a solution - a homogenous mixture of both the solvent and the solute. Water is a universal biological solvent. Its polar structure allows it to dissolve many other polar compounds. The ability of water to dissolve is governed by a balance between water molecules binding to each other and binding to the solute.
A...
68.8K
Enthalpy of Solution02:39

Enthalpy of Solution

28.4K
There are two criteria that favor, but do not guarantee, the spontaneous formation of a solution:
28.4K
In Vitro Drug Dissolution: Alternative Methods01:17

In Vitro Drug Dissolution: Alternative Methods

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Alternative drug dissolution methods include the rotating bottle, intrinsic dissolution test, peristalsis, and the Franz diffusion cell method. The rotating bottle method involves meticulously rotating tightly capped controlled-release beads in a temperature-controlled bath. Periodic decanting of samples allows for residue assay, followed by refilling with fresh medium and testing at various pH levels to emulate the gastrointestinal tract conditions.In contrast, the intrinsic dissolution test...
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Related Experiment Video

Updated: Nov 22, 2025

Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper
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Preparation of Expanded Chitin Foams and their Use in the Removal of Aqueous Copper

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Ecofriendly Method to Dissolve Chitosan in Plain Water.

Boxuan Li1,2, Juan Wang1, Mahmoud E Moustafa1

  • 1Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, Virginia 23219, United States.

ACS Biomaterials Science & Engineering
|January 8, 2021
PubMed
Summary

Researchers developed an eco-friendly method to dissolve chitosan in plain water, creating a stable, nanosize chitosan pseudosolution. This breakthrough enhances chitosan

Keywords:
chitosandissolution methodionic liquidplain water-based solutionpseudosolution

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Area of Science:

  • Polymer Science
  • Biomaterials Engineering
  • Green Chemistry

Background:

  • Chitosan, an abundant natural polymer, faces solubility challenges in plain water.
  • Limited water solubility restricts chitosan's use in biomedical applications.

Purpose of the Study:

  • To develop an eco-friendly method for dissolving chitosan in plain water.
  • To create a stable, nanosize chitosan dispersion for enhanced applications.

Main Methods:

  • Dissolving chitosan in an ionic liquid.
  • Freezing the solution overnight at -20 °C.
  • Performing solvent exchange with plain water at room temperature.

Main Results:

  • A stable, water-based chitosan pseudosolution with nanosize particles was successfully obtained.
  • The developed method is confirmed to be eco-friendly.
  • Improved quality and processability of chitosan solutions were achieved.

Conclusions:

  • This novel method overcomes chitosan's water solubility limitations.
  • The eco-friendly process facilitates broader biomedical and bioprocessing applications of chitosan.
  • The resulting nanosize chitosan dispersion offers enhanced material properties.