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Updated: Nov 22, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Psychological effects caused by COVID-19 pandemic on pregnant women: A systematic review with meta-analysis
Si Fan1, Jianping Guan2, Li Cao2
1School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Aim:
This study aimed to investigate and monitor the mental health status of pregnant women during the COVID-19 pandemic.
Materials And Methods:
The meta-analysis was used to study the literatures on the psychology of pregnant women in four databases until Sep 27, 2020.
Results:
A total of 19 articles were included in the final meta-analysis. The overall prevalence of anxiety was 42 % (95 %CI 26 %-57 %) with substantial heterogeneity (I2 = 99.6 %). The overall prevalence of depression was 25 % (95 %CI 20 %-31 %) with substantial heterogeneity (I2 = 97.9 %). Age, family economic status, social support, and physical activity seem to correlate with the mental health status of pregnant women.
Conclusion:
The prevalence of anxiety and depression among pregnant women increased significantly during the COVID-19 epidemic. Pregnant women are more concerned about others than themselves during COVID-19, and younger pregnant women seem to be more prone to anxiety, while social support and physical activity can reduce the likelihood of anxiety and depression. It is necessary to take some psychological intervention measures for pregnant women to help them go through this special period safely and smoothly.
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