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Dietary Intake and Elevated C-Reactive Protein Levels in US Military Veterans
Stephanie D Ansley1,2, Jeffrey T Howard1,2
1Department of Public Health, University of Texas at San Antonio, San Antonio, TX 78249, USA.
Insights
Deployed military veterans show higher high sensitivity C-reactive protein (hs-CRP) levels, indicating elevated inflammation, compared to civilians. This association persists regardless of diet, suggesting military stressors may impact cardiovascular health.
Area of Science:
- Biomedical Science
- Public Health
- Epidemiology
Background:
- Elevated high sensitivity C-reactive protein (hs-CRP) is linked to cardiovascular disease (CVD) pathogenesis.
- Limited research exists on dietary impacts on hs-CRP in large, diverse populations, especially minority military groups.
- Understanding these associations is crucial for targeted health interventions.
Purpose of the Study:
- To investigate the relationship between dietary intake, health behaviors, and hs-CRP levels in former military personnel.
- To examine if these associations differ across racial and ethnic groups.
- To assess the impact of military service on inflammatory markers.
Main Methods:
- Utilized data from the National Health and Nutrition Examination (NHANES) 2015-2018 waves.
- Employed a complex, multistage, probability sample design for national representativeness.
- Conducted multivariable adjustments to control for confounding factors.
Main Results:
- Previously deployed military service members exhibited a higher prevalence of clinically elevated hs-CRP compared to civilians.
- These differences in hs-CRP persisted between deployed veterans and civilians even after multivariable adjustment.
- Overweight and obese individuals showed elevated hs-CRP compared to normal BMI individuals; dietary factors did not alter veteran status associations.
Conclusions:
- Deployed military service members have a higher prevalence of elevated hs-CRP, suggesting increased inflammation.
- Dietary intake did not explain the heightened hs-CRP levels observed in veterans.
- Further research is needed to explore the role of military-specific stressors in adverse health outcomes for this population.
Abstract:
Elevated inflammatory markers, such as high sensitivity C-reactive protein (hs-CRP), have been associated with the pathogenesis of cardiovascular disease (CVD)-related diseases. However, limited studies have evaluated the potential association between dietary consumption and hs-CRP levels in a large, nationally representative sample, and fewer have investigated their role in ethnic and racial minority military populations. The goal of this study is to explore the relationship between dietary intake, health behaviors, and hs-CRP in individuals with prior military status and whether these associations differ by race/ethnicity. A complex, multistage, probability sample design was used from the National Health and Nutrition Examination (NHANES) 2015-2018 waves. Our results indicate that previously deployed military service members had a higher prevalence of clinically elevated hs-CRP levels than civilians. Differences in hs-CRP among deployed veterans and civilians remained even after multivariable adjustment. Individuals classified as overweight and obese demonstrated clinically elevated hs-CRP levels compared with those with a normal body mass index (BMI). Dietary factors did not attenuate the association between changes in hs-CRP levels and veteran status. These findings suggest the need for further investigation into how military-specific stressors contribute to unfavorable health outcomes for the military population.
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