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Lichen sclerosus et atrophicus and autoimmunity--a study of 350 women
R H Meyrick Thomas1, C M Ridley, D H McGibbon
1Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.
The British Journal of Dermatology
|January 1, 1988
Abstract:
A study of autoimmune related phenomena in 350 women with histologically confirmed lichen sclerosus et atrophicus revealed that 21.5% had one or more autoimmune related diseases, 21% had one or more first degree relatives with an autoimmune-related disease, 42% had an autoantibody at a titre greater than 1:20, and 59.5% had one or more of these autoimmune-related phenomena. No statistically significant differences in the natural history of lichen sclerosus et atrophicus were demonstrated between those patients with autoimmune-related phenomena and those without.