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Polymorphic light eruption sine eruption.

J S Dover1, J L Hawk

  • 1Department of Photobiology, St Thomas's Hospital, London, U.K.

The British Journal of Dermatology
|January 1, 1988
PubMed
Summary
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A new skin condition, polymorphic light eruption sine eruptione (PLESE), causes intense itching on sun-exposed skin without a visible rash. This variant of polymorphic light eruption (PLE) effectively responds to phototherapy treatments.

Area of Science:

  • Dermatology
  • Photodermatology

Background:

  • Polymorphic light eruption (PLE) is a common photodermatosis characterized by various skin rashes upon sun exposure.
  • A subset of patients may experience sun-induced symptoms without the typical cutaneous eruption.

Purpose of the Study:

  • To describe a previously unreported variant of PLE characterized by pruritus without rash.
  • To investigate the clinical features, potential triggers, and effective treatments for this condition, termed polymorphic light eruption sine eruptione (PLESE).

Main Methods:

  • Case series describing seven patients with intense pruritus on sun-exposed skin.
  • Clinical observation, patient history, and response to phototherapy (UVB and PUVA).
  • Exclusion of other causes of photosensitivity and pruritus.

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Main Results:

  • Seven patients (4 female, 3 male) presented with intense, non-rash pruritus on sun-exposed skin.
  • Four patients also experienced typical PLE, but pruritus alone was more common.
  • One patient showed pruritus after simulated solar irradiation, and another after PUVA therapy.
  • Low-dose UVB phototherapy and PUVA therapy were effective treatments.

Conclusions:

  • Polymorphic light eruption sine eruptione (PLESE) is a distinct clinical variant of PLE.
  • PLESE is characterized by sun-induced pruritus without a visible rash.
  • Phototherapy represents an effective treatment modality for PLESE.