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Thrombotic events in COVID-19 patients: A case series and literature review

Zahra Javidarabshahi1, Shohre Khatami2, Roxana Rezazade2

  • 1Lung Diseases Research Center, Mashhad University of Medical Science, Mashhad, Iran.

Caspian Journal of Internal Medicine
|January 11, 2021
PubMed

Insights

Coronavirus disease 2019 (COVID-19) increases the risk of thrombotic events, including pulmonary embolism, deep vein thrombosis, stroke, and myocardial infarction. This suggests a hyper-coagulative state in patients with COVID-19.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Vascular Medicine

Background:

  • The clinical manifestations of Coronavirus disease 2019 (COVID-19) are diverse and not fully understood.
  • COVID-19 has rapidly become a global pandemic with significant health implications.

Observation:

  • This case series details six patients diagnosed with COVID-19 who experienced thrombotic events.
  • Diagnoses included pulmonary thromboembolism (3 patients), deep vein thrombosis (1 patient), cerebrovascular accident (1 patient), and myocardial infarction (1 patient).

Findings:

  • COVID-19 patients exhibited a range of thrombotic complications.
  • Diagnostic methods included computed tomography (CT) angiography, Doppler ultrasonography, brain CT, and electrocardiogram.

Implications:

  • COVID-19 may predispose patients to thrombotic conditions.
  • A hyper-inflammatory and hyper-coagulative state could be responsible for these events.
  • Further prospective research is warranted to validate these observations.
Abstract

Keywords:
Coronavirus Disease 2019Myocardial InfarctionPulmonary ThromboembolismThrombosisVenous Thrombosis.

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