Mapping musical automatism: Further insights from epileptic high-frequency oscillation analysis
1Behavioral Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.
Neurology and Clinical Neuroscience
|January 11, 2021
Summary
This study examines ictal humming, a rare epilepsy symptom, revealing its origin in the non-dominant left anterior medial temporal region. High-frequency oscillation patterns helped identify the epileptogenic zone, aiding surgical planning for this musical automatism.
Area of Science:
- Neurology
- Epileptology
- Neurophysiology
Background:
- Ictal semiology is increasingly linked to epileptogenic networks.
- High-frequency oscillations (HFOs) aid in mapping these networks for surgical planning.
- Musical automatisms, including ictal humming, are rare epilepsy phenomena not well-studied regarding HFO propagation.
Purpose of the Study:
- To investigate the high-frequency oscillation propagation patterns in a rare case of epilepsy with ictal humming.
- To elucidate the epileptogenic zone associated with musical automatisms.
- To assess the utility of HFO mapping in surgical planning for such cases.
Main Methods:
- Case report of intractable epilepsy with ictal humming.
- Analysis of ictal semiology and high-frequency oscillation propagation patterns.
- Electrophysiological mapping to identify the epileptogenic zone.
Main Results:
- The epileptogenic zone was localized to the non-dominant left anterior medial temporal region.
- Ictal humming was associated with specific high-frequency propagation patterns.
- Mapping facilitated treatment and confirmed localization to a non-dominant frontal-temporal network.
Conclusions:
- Musical automatisms, like ictal humming, can localize to non-dominant frontal-temporal networks.
- High-frequency oscillation propagation patterns are valuable for understanding and surgical planning of rare epilepsy phenomena.
- This case supports prior observations on the network localization of musical automatisms.
