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Conductive Metal-Organic Frameworks for Amperometric Sensing of Paracetamol
Jing Wang1,2, Sen Liu1, Jiahuan Luo1
1Henan Joint International Research Laboratory of Nanocomposite Sensing Materials, School of Chemical and Environmental Engineering, Anyang Institute of Technology, Anyang, China.
Abstract:
An electrochemical sensor for paracetamol is executed by using conductive MOF (NiCu-CAT), which is synthesized by 2, 3, 6, 7, 10, 11-hexahydroxytriphenylene (HHTP) ligand. The utility of this 2D NiCu-CAT is measured by the detection of paracetamol, p-stacking within the MOF layers is essential to achieve high electrical conductivity, redox activity, and catalytic activity. In particular, NiCu-CAT demonstrated detection Limit of determination near 5μM for paracetamol through a wide concentration range (5-190 μM). The NiCu-CAT/GCE exhibits excellent reproducibility, stability, and interference for paracetamol.
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