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iPSC for modeling neurodegenerative disorders

Valeria Valadez-Barba1, A Cota-Coronado1,2, O R Hernández-Pérez1

  • 1Department of Medical and Pharmaceutical Biotechnology, Center for Research and Assistance in Technology and Design of the State of Jalisco, A.C. Av. Normalistas 800, Colinas de las Normal, Jalisco, Mexico, P.C.44270.

Regenerative Therapy
|January 11, 2021
PubMed

Keywords:
AD, Alzheimer's diseaseAFP, Alpha-FetoproteinAlzheimerAβ, β-AmyloidB-III-TUB, β–III–TubulinBBB, Blood Brain BarrierCRISPR, Clustered Regularly Interspaced Short Palindromic RepeatsDOPAL, 3,4-DihydroxyphenylacetaldehydeEBs, Embryoid BodiesFLASH, Fast Length Adjustment of Short ReadsLUHMES, Lund Human Mesencephalic Cell LineMHC, Mayor Histocompatibility ComplexNeurodegenerative diseasaesPCR, Polymerase Chain ReactionPD, Parkinson's DiseaseParkinsonROS, Reactive Oxygen SpeciesSCs, Stem CellsSMA, Smooth-Muscle AntibodySNPc, Substantia Nigra Pars CompactaTH, Tyrosine HydroxylaseWGS, Whole Genome SequencinggRNA, guide RNAhESC, Human Embryonic Stem CellsiPSCsiPSCs, Induced Pluripotent Stem CellsnsSNVs, nonsynonymous single nucleotide variantspTau, Phosphorylated Tau

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