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Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.5K

Chest CT features associated with the clinical characteristics of patients with COVID-19 pneumonia

Ruichao Niu1, Shuming Ye2, Yongfeng Li3

  • 1Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, PR China.

Annals of Medicine
|January 11, 2021
PubMed

Insights

Chest CT scans reveal distinct patterns in COVID-19 patients, aiding in prognosis. Nodular patterns often indicate non-severe cases with better outcomes, while mixed patterns suggest severe disease and poorer prognosis.

Area of Science:

  • Radiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic.
  • Chest CT imaging is crucial for diagnosing and monitoring COVID-19.
  • Understanding CT findings' correlation with clinical characteristics is vital.

Purpose of the Study:

  • To investigate the relationship between chest CT findings and clinical characteristics in COVID-19 patients.
  • To explore how CT features correlate with disease severity and prognosis.

Main Methods:

  • Retrospective enrollment of 361 COVID-19 patients confirmed by RT-PCR or next-generation sequencing.
  • Analysis of serial chest CT procedures (more than 4 per patient).
  • Categorization of CT findings including ground-glass opacities, consolidation, nodules, fibrous stripes, and mixed patterns.

Main Results:

  • Initial CT scans showed bilateral lung lesions, predominantly peripheral.
  • Ground-glass opacities (28.5%), nodules (23.0%), and mixed patterns (30.2%) were common.
  • Mixed patterns were associated with severe cases (21.1%), while nodules were linked to non-severe cases (2.4%).
  • Follow-up CT revealed significantly lower total severity scores for nodular and fibrous stripe patterns compared to mixed patterns (p < .01).

Conclusions:

  • Chest CT findings are instrumental in diagnosing and predicting COVID-19 patient outcomes.
  • Nodular CT patterns correlate with non-severe cases and favorable prognosis.
  • Mixed CT patterns are more frequent in severe cases, indicating a poorer prognosis.
Abstract

Keywords:
COVID-19SARS-CoV-2 imaging featurescomputed tomographypneumonia

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