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Updated: Nov 22, 2025

Fast Micro-iontophoresis of Glutamate and GABA: A Useful Tool to Investigate Synaptic Integration
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Temperature regulates synaptic subcellular specificity mediated by inhibitory glutamate signaling

Mengqing Wang1, Daniel Witvliet2,3, Mengting Wu1

  • 1Department of Neurosurgery, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Zhongshan Hospital, Fudan University, Shanghai, China.

Plos Genetics
|January 11, 2021
PubMed
Summary

High temperatures disrupt synaptic connections in C. elegans AIY interneurons via glutamate signaling. This study reveals a novel mechanism for temperature-induced neurological defects.

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