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Cloning and sequencing of cDNA that encodes goat growth hormone
Y Yamano1, K Oyabayashi, M Okuno
1Department of Agricultural Chemistry, Kyoto University, Japan.
FEBS Letters
|February 15, 1988
Abstract:
The cDNA that encodes goat growth hormone (gGH) was isolated from a goat pituitary cDNA library. The cDNA, about 880 base pairs long, had a coding sequence, 5'- and 3'-untranslated regions and a poly(A) chain. The cDNA could encode a polypeptide of 217 amino acids. The amino acid sequence homology between gGH and the sequences of bovine GH, rat GH and human GH was 99, 83 and 66%, respectively. By Northern blot hybridization, we found that the possible gGH gene is transcribed in the goat pituitary.