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Noncatalytic protein component of elastase from horse leucocytes. A protein with regulatory function
J Potempa1, E Korzus, J Silberring
1Institute of Molecular Biology, Jagiellonian University, Cracow, Poland.
The International Journal of Biochemistry
|January 1, 1988
Abstract:
1. Noncatalytic protein component (NPC), a strongly acidic protein (pH = 4.5) was separated from native horse leucocyte elastase 1. 2. This protein reduces elastinolytic properties of elastases: 1 and 2A probably by decreasing their isoelectric points. 3. A possible regulatory role of this protein may be inferred from a higher affinity of elastase 1 to NPC rather than to elastin.