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Published on: April 18, 2013
Milk of calcium pericardial effusion confirmed with postmortem computed tomography and autopsy findings: A case
Kenji Ninomiya1, Tsuneo Yamashiro2, Maki Fukasawa1
1Department of Legal Medicine, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, Japan.
Insights
This study details a rare case of milk of calcium pericardial effusion leading to fatal constrictive epicarditis. Postmortem imaging and autopsy confirmed the findings, highlighting a unique cause of heart failure.
Area of Science:
- Cardiology
- Radiology
- Pathology
Background:
- Constrictive epicarditis can lead to heart failure.
- Milk of calcium pericardial effusion is a rare condition.
Observation:
- A 60-year-old male presented with cardiopulmonary arrest and subsequent death.
- Clinical symptoms included neck swelling and cough.
- Postmortem computed tomography (CT) revealed highly dense pericardial fluid and epicardial/pericardial calcifications.
Findings:
- Autopsy confirmed thickened, calcified epicardium and pericardium with adhesions.
- Pericardial fluid was viscous and turbid.
- Group G β-hemolytic streptococci were identified in pericardial fluid cultures.
- The cause of death was diagnosed as heart failure secondary to constrictive epicarditis.
Implications:
- This is the first reported case of milk of calcium pericardial effusion confirmed by postmortem CT and autopsy.
- The findings contribute to understanding rare causes of constrictive epicarditis and heart failure.
- Highlights the utility of advanced imaging in postmortem examinations.
Abstract:
We present the postmortem computed tomography and autopsy findings of a 60-year-old man who developed milk of calcium pericardial effusion and died of constrictive epicarditis. He experienced out-of-hospital cardiopulmonary arrest, and spontaneous circulation returned at the hospital. However, 7 h after recovery, the patient died. He had a swollen neck, had been experiencing coughing from 4 to 5 days earlier, and had no significant medical or surgical history. On computed tomography (CT), highly dense pericardial fluid (CT value: 130-150 Hounsfield units) and multiple calcifications along the epicardium and pericardium were visualized. The epicardium and pericardium were thick, hard, rough, and widely calcified with mild adhesions on autopsy. The pericardial cavity contained a pale, reddish brown, turbid, and highly viscous liquid. Bacteriological tests of pericardial fluid cultures revealed the presence of group G β-hemolytic streptococci. Hence, we diagnosed the patient's cause of death as heart failure due to constrictive epicarditis. We believe that this case of milk of calcium pericardial effusion is the first case confirmed with postmortem CT and autopsy findings.
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